Your GeneMate® test result is only directly applicable to you but may have implications for your family as well. Variants found through GeneMate® are most often inherited from a parent. In this case, your siblings have a 50% chance of carrying the same variant. Your children also have a 50% chance of carrying the variant. In rare cases the variant may be newly occurring (also called a de novo variant), in which case your parents and siblings are not carriers. Children, however, can inherit the variant.
Upon visiting a cancer genetics clinic, the inheritance pathway will be investigated to determine if and from whom the variant was inherited, and which of your relatives should be tested. These relatives may be offered a carrier test, a test that looks specifically for the variant you carry.